Zimax Suspension is a kind of antibiotic. It is widely prescribed to children to treat a variety of bacterial infections that affect the ear, eyes, nose, throat, lungs, skin, and gastrointestinal tract.
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Zimax Suspension is a medication containing Azithromycin, which is a type of Macrolide antibiotic used to treat bacterial infections in children. It is effective in treating various infections such as chest, throat, and nasal infections including bronchitis, pneumonia, tonsillitis, sore throat, and sinusitis. It is also used to treat ear infections, skin, and soft tissue infections, and sexually transmitted diseases caused by organisms such as chlamydia trachomatis/ Neisseria gonorrhea in affected children.
However, it is not recommended for use in children allergic to azithromycin, other macrolides, and/or ketolides. It is important to inform the doctor if the child has any medical conditions such as diabetes, myasthenia gravis, heart problems, liver problems, or kidney problems before administering Zimax Suspension.
Zimax Suspension is only used in children and adolescents below 18 years and is not recommended for use in pregnant or breastfeeding women or elderly patients. The medication may cause common side effects in children such as stomach cramps, nausea, diarrhea, flatulence, dizziness, headache, skin rash, or itching. If these symptoms worsen, it is recommended to consult the doctor.
Zimax Suspension is not recommended for use in pregnant women as it is used only in children.
Zimax Suspension is not recommended for use in pregnant women as it is used only in children.
Zimax Suspension is not recommended for use in pregnant women as it is used only in children.
There are no data available about the influence of Zimax Suspension on the ability to drive or operate machines. However, Zimax Suspension may cause dizziness and seizures so make sure you are not affected before driving or operating machinery.
Zimax Suspension should be administered with caution in children with kidney problems such as impaired renal function. Consult your doctor before administering the medicine to the child.
Zimax Suspension should be administered with caution in children with liver problems such as impaired hepatic function. Consult your doctor before administering the medicine to the child.
works by reducing bacterial protein synthesis (which is required for the bacterium to proliferate), resulting in its death and so stopping its growth and infection spread in afflicted individuals.
Used in pediatric patients:
Azithromycin can be taken orally without the need for protection from stomach acids since it is acid-stable. The drug is rapidly absorbed, and its absorption is more noticeable on an empty stomach. Peak concentration is typically reached in 2.1 to 3.2 hours for oral forms in adults. Azithromycin is effectively transported to the site of infection due to its high concentration in phagocytes. It is highly lipid soluble and can be caught by particles, leading to its concentration in tissues being over 50 times higher than in plasma.
A single large dose of azithromycin can maintain bacteriostatic levels in infected tissue for several days because of its long half-life. The mean apparent plasma clearance is 630 mL/min, and the terminal elimination half-life is 68 hours after a single 500 mg dose. The drug's significant absorption and subsequent release from tissues prolong the terminal half-life. Biliary excretion is one of the primary elimination pathways for azithromycin, with urinary excretion accounting for about 6% of the prescribed dose.
Examples of gram-positive, facultative, aerobic bacteria susceptible to azithromycin include Staphylococcus aureus, Streptococcus agalactiae, Streptococcus pneumoniae, and Streptococcus pyogenes. Examples of gram-negative, aerobic, and facultative bacteria include Neisseria gonorrhoeae, Haemophilus influenzae, Moraxella catarrhalis, and Haemophilus ducreyi. Non-bacterial microorganisms, such as Mycoplasma pneumoniae, Chlamydia pneumoniae, and Chlamydia trachomatis, are also susceptible to azithromycin. The production of beta-lactamase should not affect azithromycin's efficacy. Gram-positive, aerobic, and facultative bacteria from the Streptococcus genus (Groups C, F, and G) and from the Viridans genus are also susceptible to azithromycin.
This medication can be taken orally in tablet or suspension form, with or without food depending on the type of medication. The oral suspension should be used within 10 days after reconstitution. The extended-release oral suspension should be taken on an empty stomach within 12 hours of reconstitution and is only given in a single dose.
Administer Zimax Suspension to the kid as directed by your doctor. Shake vigorously before using. The specific amount and length of treatment for your kid will be determined by your doctor based on the child's age, body weight, and medical status.
ZiMax absorption is lowered when food and antacids are present. ZiMax should not be used in patients who are receiving ergot alkaloids because it may cause ergotism due to an interaction between azithromycin and the cytochrome P-450 system. When administering digoxin and cyclosporin at the same time, care should be taken because macrolides raise their plasma concentrations. Azithromycin does not interact with Warfarin, Theophylline, Carbamazepine, Methylprednisolone, or Cimetidine.
Patients who are hypersensitive to azithromycin or any other macrolide antibiotic should avoid taking it. Ergot derivatives and azithromycin should not be taken together. Patients with hepatic disorders should avoid azithromycin.
Zimax belongs to category B for use during pregnancy. Animal studies have shown that Azithromycin does not have any harmful effects on the developing fetus. However, there is not enough research on pregnant women to confirm its safety. Therefore, Azithromycin should only be used during pregnancy if it is absolutely necessary and there are no other options available.
It is not known whether Zimax is present in breast milk. Hence, if Azithromycin is given to a nursing woman, caution should be exercised.
Protect from light and moisture by storing in a cool, dry place below 30°C. Keep out of children's reach.
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